Estriol Cream

About Estriol Cream?

Estriol Cream is a type of hormone replacement therapy (HRT) used to treat symptoms of vaginal atrophy in postmenopausal women. It contains estriol, a mild form of estrogen, and is applied directly inside the vagina. This helps relieve discomfort such as dryness, itching, burning, and pain during intercourse caused by low estrogen levels after menopause. Estriol cream works locally, meaning it has minimal absorption into the bloodstream, reducing the risk of systemic side effects. 

How and when to take Estriol Cream?

Estriol Cream is typically used at bedtime, allowing it to be absorbed while you rest. The cream is inserted into the vagina using a special applicator, and your doctor will usually advise daily use at first, followed by a reduced frequency—such as two or three times a week—for maintenance. It’s important to use it consistently and exactly as prescribed, as this helps relieve symptoms like dryness, irritation, or discomfort.

How long does Estriol Cream last?

Estriol cream works locally and provides symptom relief for about 24 hours, which is why it’s often used daily at first. Once symptoms improve, it may be used just a few times a week for ongoing relief. The full course of treatment can last several weeks to months, depending on individual needs.

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